FLEX TIPS PUBLICATIONS & ABSTRACTS

FLEX TIPS Data


Evidence / FLEX TIPS

FLEX: A Real-World Evidence, Full Transcriptome Study in 30,000 Patients With Early-Stage Breast Cancer

Title: FLEX: A Real-World Evidence, Full Transcriptome Study in 30,000 Patients With Early-Stage Breast CancerBackground: The advent of subtype-specific treatments, particularly hormone therapies and HER2-targeted therapies, has significantly improved survival rates and quality of life for breast cancer (BC) patients.  Over the last decade genomic signatures have enabled improved classification Read More

FLEX: 30K Full Transcriptome, Real-World Evidence Database for Early-Stage Breast Cancer, and Investigator-Initiated Protocols

Publication: ASCO 2023, Abstract #TPS621 Authors: Eric A. Brown1; Linsey P. Gold1; Carl R. Gray2; Douglas K. Marks3; Vibha T. Thomas4; Alfredo A. Santillan5; Cynthia Ma6; Ciera Singleton7; William Audeh7; on behalf of the FLEX Investigators Group 1. Comprehensive Breast Care, Troy, MI; 2. Utah Hem Onc, Ogden, UT; 3. Perlmutter Cancer Center, NYU Langone Health, New York, NY; 4. Texas Oncology-Flower Mound, Flower Mound, TX; 5. Texas Oncology PA, San Antonio, TX; 6. Washington University School of Medicine, St. Louis, MO; 7. Agendia Inc., Irvine, CA.

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MammaPrint, BluePrint, and Full-genome Data Linked with Clinical Data to Evaluate New Gene EXpression Profiles (FLEX): A real-world dataset and investigator-initiated protocols in ESBC

  Publication: St. Gallen Authors: Jennifer A. Crozier, Lisa Blumencranz, Miranda Kleijn, Heather Kling, Amy M. Truitt, Darina Proni, Christine Finn, William Audeh, Bastiaan van der Baan, FLEX Investigators’ Group Background: The personalized management of early-stage breast cancers is enhanced by the ability of genomic signatures to stratify tumors into Read More

The FLEX real world data platform explores new gene expression profiles and investigator-initiated protocols in early stage breast cancer

Publication: Miami Breast Authors: Pat Whitworth, Jennifer A. Crozier, Robert Maganini, Cathy Graham, Beth-Ann Lesnikoski, Kathryn Wagner, June Lee, Julian Berrocal, Amy M. Truitt, Erin Yoder, Lisa Blumencranz, Bastiaan van der Baan, William Audeh, FLEX Investigators’ Group Background: Genomic expression profiles have implications for the personalized treatment of breast cancer Read More

The FLEX real world data platform explores new gene expression profiles and investigator-initiated protocols in early stagebreast cancer

PUBLICATION: SABCS 2020 AUTHORS: Laura Lee, Sami Diab, Julie Barone, Jennifer A. Crozier, Margret Chen, Rakshanda Layeequr Rahman, Robert Maganini, Douglas Marks, Amy M. Truitt, Lisa Blumencranz10, Erin Yoder10, William Audeh, Bastiaan van der Baan, FLEX Investigators Group Background: Genomic expression profiles have implications for the personalized treatment of Read More

ASCO 2020: FLEX Trials in Progress

PUBLICATION: ASCO 20 AUTHORS: Nina D’Abreo, Jennifer Crozier, Adam Brufsky, Ian Grady, Sami Diab, Blanche Mavromatis, Carrie Dul, Rakhshanda Layeequr Rahman, Laura Lee, Vijayakrishna K. Gadi1, Sarah Untch, Erin Yoder, Heather M. Kling, Amy M. Truitt, William Audeh, Bastiaan van der Baan, FLEX Investigators Group SUMMARY: Genomic expression profiles have Read More