MammaPrint: a test to predict risk of breast cancer recurrence
The clarity that MammaPrint delivers helps patients and physicians make informed, confident treatment management decisions.
MammaPrint is FDA-cleared for women of all ages. MammaPrint is also available via next generation sequencing on the Illumina MiSeq platform as an LDT.
The test is validated by peer-reviewed data and supported by the highest level of clinical evidence from a landmark randomized,* prospective,† phase III‡clinical trial known as MINDACT.
MammaPrint test report
MammaPrint provides a clear low risk or high risk result to better predict breast cancer recurrence
MammaPrint High Risk
MammaPrint Low Risk
-1.000 MammaPrint index (MPI) +1.000
A high risk result means that a patient has a statistically significant (11.7%) chance her cancer will recur within 5 years.1
Recommended by expert medical guidelines
MammaPrint is included in numerous clinical practice guidelines developed by world-recognized cancer care organizations. Clinical guidelines are evidence-based recommendations for healthcare professionals involved in the management of patients.
Guidelines aim to improve the quality of care and services based on the most up to date peer-reviewed evidence. For example, MammaPrint is the only test of its kind endorsed by the American Society of Clinical Oncology for lymph node-positive patients.
Also included in the National Comprehensive Cancer Network® (NCCN®).
70-Gene Assay (MammaPrint) has a Category 1 recommendation from the National Comprehensive Cancer Network® (NCCN®). Category 1 is based upon high-level evidence; there is uniform NCCN consensus that intervention is appropriate. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Breast Cancer V.1.2019. © 2019 National Comprehensive Cancer Network, Inc 2019. All rights reserved. To view the most recent and complete version of the guidelines, go to NCCN.org. NCCN makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.
70-gene Assay (MammaPrint) is the only genomic assay with FDA clearance and Level 1 evidence by the American Society of Clinical Oncology (ASCO).
Where to next?
*Randomization is a procedure to allocate clinical study participants into different groups. By using chance to allocate participants, the groups are likely to be similar and allow the effects of the treatments to be compared more fairly.† When patients are recruited to a clinical study and followed forward in time.‡ A type of clinical trial designed to confirm and expand on the safety and/or effectiveness of an intervention from earlier clinical trials. Phase III trials are often large and may consist of hundreds or even thousands of patients.
1. Drukker, C.A., et al. Int J Cancer. January 2013; 133: 929–936 (RASTER)
2. Soliman, et al. BMC Cancer (2020) 20:81.