PUBLICATIONS & ABSTRACTS: CLINICAL EVIDENCE
100s of extensive peer reviewed publications and studies utilizing MammaPrint + BluePrint have observed benefits from treatment in the following areas of clinical utility:
Scientific evidence for clinical utility.
By continually expanding and strengthening our database of proven research including 20+ years of clinical validation and 200+ research collaborations, we have gained widespread trust in the precision, accuracy and quality of our MammaPrintยฎ and BluePrintยฎ test suite.
Evidence
The 70-gene signature (MammaPrint) accurately predicts distant breast cancer recurrence risk in older patients
PUBLICATION: SABCS 2020 AUTHORS: Iris Noordhoek, Esther Bastiaannet, Ersan Lujinovic, Laura Esserman, Jelle Wesseling, Astrid Scholten, Carolien Schroders, Sjoerd Elias, Nienke de Glas, Judith Kroep, Johanneke Portielje, Miranda Kleijn, Gerrit-Jan Liefers Introduction: Adjuvant therapy for hormone receptor positive (HR+) breast cancer (BC) is guided by clinicopathological risk factors, but Read More
Prediction of benefit from adjuvant pertuzumab by BluePrint RNA sequencing in the APHINITY trial
PUBLICATION: SABCS 2020 AUTHORS:Ian E Krop, Lorenza Mittempergher, Joseph N Paulson, Fabrice Andre, Herve Bonnefo, Sherene Lo, Sibylle Lo1bl, Richard D Gelber', Carmela Caballero, Debora Fumagall, RaJ1th Bhaskaran, Christa Dreezen, Rene Bernards', Laura J van 't Veer and Martine J P1ccart Background: APHINITY is a phase Ill study (NCT01358877), which Read More
MammaPrint Guides Treatment Decisions in Breast Cancer: Results of the IMPACt Trial
Publication: Soliman et al. BMC Cancer (2020) 20:81 Authors: Hatem Soliman, Varsha Shah, Gordan Srkalovic, Reshma Mahtani, Ellis Levine, Blanche Mavromatis, Jayanthi Srinivasiah, Mohamad Kassar, Robert Gabordi, Rubina Qamar, Sarah Untch, Heather M. Kling, Tina Treece and William Audeh Title: MammaPrint guides treatment decisions in breast Cancer: results of Read More
MammaPrint and BluePrint NGS Results are Robust and Accurate for Patients with Early Stage Breast Cancer
ย PUBLICATION: AMP 2020 AUTHORS: Douglas Kingma, Kasey Lawrence, Sahra Uygun, Camila Zanette, Helen Yang, Sammy Mee, Lorenza Mittempergher, Anke Witteveen, Leonie Delahaye, Bob Chan, Annuska Glas 1. Tennessee Oncology, Nashville, TN; 2. Agendia Inc, Irvine, CA; 3. Agendia NV, Amsterdam, The Netherlands Introduction: MammaPrint (MP) and BluePrint (BP) are Read More
ESMO 2020: UltraLow Data from the IKA Cohort
PUBLICATION: ESMO 2020 AUTHORS: Mark Opdam, Vincent van der Noort, Miranda Kleijn, Anuska Glas, Ingrid Mandjes, Dinja Kruger, Paul van Diest, Jan Vermorken, Harm van Tinteren, Sabine Linn Background: Adjuvant tamoxifen is widely used as endocrine treatment for oestrogen receptor positive (ER+) breast cancers (BC). Guidelines recommend the use of Read More
ESMO 2020 – Hallmarks of Cancer
PUBLICATION: ESMO 2020 AUTHORS: Josien C. Haan, Rajith Bhaskaran, Lorenza Mittempergher, Ersan Lujinovic, William Audeh, Frederique Penault-Llorca and Annuska M. Glas Background: MammaPrintยฎ (MP) is a 70-gene based assay that stratifies early-stage breast cancer (EBC) patients into low and high-risk of relapse. BluePrintยฎ (BP) is an 80-gene based assay that Read More
Cost-effectiveness analysis of the 70-gene signature compared with clinical assessment in breast cancer based on a randomised controlled trial
PUBLICATION: European Journal of Cancer AUTHORS: Valesca P. Retel, Danalyn Byng, Sabine C. Linn, Katarzyna Jozwiak, Hendrik Koffijberg, Emiel J. Rutgers, Fatima Cardoso, Martine J. Piccart, Coralie Poncet, Laura J. van โt Veer, Wim H. van Harten. Abstract: The clinical utility of the 70-gene signature (MammaPrintยฎ) to guide chemotherapy Read More
