PUBLICATIONS & ABSTRACTS: CLINICAL EVIDENCE

100s of extensive peer reviewed publications and studies utilizing MammaPrint + BluePrint have observed benefits from treatment in the following areas of clinical utility:


Scientific evidence for clinical utility.

By continually expanding and strengthening our database of proven research including 20+ years of clinical validation and 200+ research collaborations, we have gained widespread trust in the precision, accuracy and quality of our MammaPrint® and BluePrint® test suite.

Evidence

ASCO 2020: 8q22 Poster

PUBLICATION: ASCO 20 AUTHORS: Sami Diab, Matei P. Socoteanu, Carlos A. Encarnacion, Cynthia R. C. Osborne, Carolyn B. Hendricks, Kristi McIntyre, Vibha Taneja Thomas, Rajith Bhaskaran, Josien Haan, Lorenza Mittempergher, Andrea Menicucci, William Audeh, Joyce O'Shaughnessy, FLEX Investigators’ Group SUMMARY: Previous studies have shown that CCNE2 expression is higher in Read More

ASCO 2020: HER2 Reclassification

PUBLICATION: ASCO 2020 AUTHORS: Adam Brufsky, Jennifer A. Crozier, Paul J. Chuba, Sung Ho Lee, Andrea Menicucci, Heather M. Kling, Erin Yoder, William Audeh, FLEX Investigators' Group SUMMARY: Biological heterogeneity of HER2 positive breast cancers is supported by a modest benefit of HER2- targeted therapies reported in the APHINITY and Read More

ASCO 2020: FLEX Trials in Progress

PUBLICATION: ASCO 20 AUTHORS: Nina D’Abreo, Jennifer Crozier, Adam Brufsky, Ian Grady, Sami Diab, Blanche Mavromatis, Carrie Dul, Rakhshanda Layeequr Rahman, Laura Lee, Vijayakrishna K. Gadi1, Sarah Untch, Erin Yoder, Heather M. Kling, Amy M. Truitt, William Audeh, Bastiaan van der Baan, FLEX Investigators Group SUMMARY: Genomic expression profiles have Read More

Performance Characteristics of the BluePrint® Breast Cancer Diagnostic Test

PUBLICATION: Translational Oncology Volume 13, Issue 4, April 2020, 100756 AUTHORS: Lorenza Mittempergher, Leonie JMJ Delahaye, Anke T Witteveen, Mireille HJ Snel, Sammy Mee, Bob Y Chan, Christa Dreezen, Naomi Besseling, Ernest JT Luiten, Annuska M Glas SUMMARY: The analytical performance of a multi-gene diagnostic signature depends on many parameters, Read More

Miami Breast 2020 FLEX Trials in Progress

AUTHORS: Robert Maganini, Pond Kelemen, Jennifer A. Crozier, Gordan Srkalovic, Adam Brufsky, Mehran Habibi, Ian Grady, Nina D’Abreo, Michelle Bolner, Sarah Untch, Erin Yoder, Heather M. Kling, William Audeh, Bastiaan van der Baan FLEX Investigators Group DESCRIPTION: The FLEX Real World Data Platform Explores New Gene Expression Profiles and Investigator-Initiated Read More

MammaPrint guides treatment decisions in breast Cancer: results of the IMPACt trial

PUBLICATION: Soliman et al. BMC Cancer (2020) 20:81 AUTHORS: Hatem Soliman, Varsha Shah, Gordan Srkalovic, Reshma Mahtani, Ellis Levine, Blanche Mavromatis, Jayanthi Srinivasiah, Mohamad Kassar, Robert Gabordi, Rubina Qamar, Sarah Untch, Heather M. Kling, Tina Treece1, William Audeh SUMMARY: Results from the IMPACt trial measured changes in both treatment decisions Read More