PUBLICATIONS & ABSTRACTS: CLINICAL EVIDENCE
100s of extensive peer reviewed publications and studies utilizing MammaPrint + BluePrint have observed benefits from treatment in the following areas of clinical utility:
Scientific evidence for clinical utility.
By continually expanding and strengthening our database of proven research including 20+ years of clinical validation and 200+ research collaborations, we have gained widespread trust in the precision, accuracy and quality of our MammaPrint® and BluePrint® test suite.
Evidence
Impact of Neoadjuvant Endocrine Therapy on Tumor Transcriptome in Patients With Early-Stage Breast Cancer From the FLEX Trial
PUBLICATION: San Antonio Breast Cancer Symposium 2022 TITLE: Impact of neoadjuvant endocrine therapy on tumor transcriptome in patients with early-stage breast cancer from the FLEX trial AUTHORS: Mehran Habibi1, Danijela Jelovac1, Rima Couzi1, Cesar Agusto Santa-Maria1, Catherine Klein1, Marissa White1, Nivali Naik1, Jennifer Wei2, Yen Huynh2, Architha Ellappalayam3, Lisa Read More
FOCUS Trial: Validation of MammaPrint for ≥ 70yrs w/ UltraLow risk of distant recurrence
J Geriatr Oncol. 2022 Nov;13(8):1172-1177 Authors: Noordhoek et al.
Read MoreSTO-5 Trial: 20-yr benefit from Adjuvant Goserelin & Tamoxifen, JCO 2022
Journal of Clinical Oncology, 40:4071-4082 Authors: Johansson et al.
Read MoreI-SPY2: ImPrint immune signature identifies ESBC patients who benefit from PD1 checkpoint inhibition
ASCO 2022, Poster #514 Authors: Kuilman et al.
Read MoreIKA Trial: MammaPrint UltraLow & Limited Systemic Endocrine Overtreatment
IKA Trial, Breast Cancer Res Treat, 2022; 194(2): 265-278 Authors: Opdam, et al.
Read MoreBudget impact analysis for the Health Care Package by using MammaPrint in Belgium
Publication: ESMO BREAST CANCER CONGRESS 2022 Authors De Lameillieure K (1), Van der Meijden C (1), Klinkhamer J (1) , Cusumano P (2). 1- Medical & Clinical Affairs, Agendia NV., Amsterdam, Netherlands, 2 - Breast Clinic, Centre Hospitalier Chrétien, Liège, Belgium Background & Objective Gene expression profiling (GEP) tests, Read More
Equivalence of NGS-based MammaPrint 70-gene signature risk of recurrence and BluePrint 80-gene signature of molecular subtyping tests to the centralized microarray tests
Publication: ESMO BREAST CANCER CONGRESS 2022 Authors Esther Schuler(1), Sahra Uygun(2), Lorenza Mittempergher(3), Darina Pronin(3), Sammy Mee(2), Simon Bao(2), Tyson Cavness(2), Anke Witteveen(3), and Annuska Glas(3) 1. Zotz|Klimas, MVZ Düsseldorf-Centrum GbR, Germany 2. Agendia Inc., Irvine, CA 3. Agendia NV., Amsterdam, Netherlands Background The MammaPrint® 70-gene signature (70GS) risk Read More
