ADJUVANT PUBLICATIONS & ABSTRACTS
Adjuvant data
Evidence / Adjuvant
Controlling Technical Variation Amongst 6693 Patient Microarrays of the Randomized MINDACT Trial
PUBLICATION: Communications Biology AUTHORS: Laurent Jacob, Anke Witteveen, Inès Beumer, Leonie Delahaye, Diederik Wehkamp, Jeroen van den Akker, Mireille Snel, Bob Chan, Arno Floore, Niels Bakx, Guido Brink, Coralie Poncet, Jan Bogaerts, Mauro Delorenzi, Martine Piccart, Emiel Rutgers, Fatima Cardoso, Terence Speed, Laura van ’t Veer, and Annuska Glas Abstract: Read More
ASCO 2020: 8q22 Poster
PUBLICATION: ASCO 20 AUTHORS: Sami Diab, Matei P. Socoteanu, Carlos A. Encarnacion, Cynthia R. C. Osborne, Carolyn B. Hendricks, Kristi McIntyre, Vibha Taneja Thomas, Rajith Bhaskaran, Josien Haan, Lorenza Mittempergher, Andrea Menicucci, William Audeh, Joyce O'Shaughnessy, FLEX Investigators’ Group SUMMARY: Previous studies have shown that CCNE2 expression is higher in Read More
MammaPrint guides treatment decisions in breast Cancer: results of the IMPACt trial
PUBLICATION: Soliman et al. BMC Cancer (2020) 20:81 AUTHORS: Hatem Soliman, Varsha Shah, Gordan Srkalovic, Reshma Mahtani, Ellis Levine, Blanche Mavromatis, Jayanthi Srinivasiah, Mohamad Kassar, Robert Gabordi, Rubina Qamar, Sarah Untch, Heather M. Kling, Tina Treece1, William Audeh SUMMARY: Results from the IMPACt trial measured changes in both treatment decisions Read More
SABCS 2019: Cyclin E Expression
AUTHORS: Lorenza Mittempergher, Joseph McKelley, Rajith Bhaskaran, Sahra Uygun, René Bernards, Laura J van ’t Veer, Annuska M Glas, Cynthia X Ma, William Audeh DESCRIPTION: Cyclin E overexpression is associated with High Risk 70-gene signature, and may indicate intrinsic resistance to CDK4/6 inhibitors The use of CDK4/6 inhibitors (CDK4/6i) is Read More
SABCS 2019: PROMIS Clinical Risk
AUTHORS: Michaela Tsai, Hatem Soliman, Shelly Lo, Rubina Qamar, Raye Budway, Ellis Levine, Pat Whitworth, Blanche Mavromatis, Robin Zon, Sarah Untch1, Lisa Blumencranz, Joseph McKelley, William Audeh, PROMIS Investigators Group DESCRIPTION: Treatment recommendations in ER+ patients ≤ 50 years: comparison of the 21-gene assay and 70-gene signature in the PROMIS Read More
Prospective Validation of a Genomic Assay in Breast Cancer: The 70-Gene MammaPrint Assay and the MINDACT Trial
PUBLICATION: Acta Medica Academica. Volume 48 (2) August 2019 AUTHOR: William Audeh, MD SUMMARY: A narrative review of the MINDACT trial. Read more: Audeh_2019_Acta Medica Academica_Prospective Validation of a Genomic Assay...
Role of Patient and Disease Factors in Adjuvant Systemic Therapy Decision Making for Early-Stage, Operable Breast Cancer: Update of the ASCO Endorsement of the Cancer Care Ontario Guideline
PUBLICATION: Journal of Clinical Oncology 37, no. 22 (August 01, 2019) 1965-1977. DOI: 10.1200/JCO.19.00948. AUTHORS: N. Lynn Henry, MD, PhD; Mark R. Somerfield, PhD; Vandana G. Abramson, MD; Nofisat Ismaila, MD; Kimberly H. Allison, MD; Carey K. Anders, MD; Diana T. Chingos, MS, MFA; Andrea Eisen, MD; Bruno L. Ferrari, Read More