PUBLICATIONS & ABSTRACTS: CLINICAL EVIDENCE

100s of extensive peer reviewed publications and studies utilizing MammaPrint + BluePrint have observed benefits from treatment in the following areas of clinical utility:


Scientific evidence for clinical utility.

By continually expanding and strengthening our database of proven research including 20+ years of clinical validation and 200+ research collaborations, we have gained widespread trust in the precision, accuracy and quality of our MammaPrint® and BluePrint® test suite.

Evidence

Miami Breast 2020 FLEX Trials in Progress

AUTHORS: Robert Maganini, Pond Kelemen, Jennifer A. Crozier, Gordan Srkalovic, Adam Brufsky, Mehran Habibi, Ian Grady, Nina D’Abreo, Michelle Bolner, Sarah Untch, Erin Yoder, Heather M. Kling, William Audeh, Bastiaan van der Baan FLEX Investigators Group DESCRIPTION: The FLEX Real World Data Platform Explores New Gene Expression Profiles and Investigator-Initiated Read More

SABCS 2019: Cyclin E Expression

AUTHORS: Lorenza Mittempergher, Joseph McKelley, Rajith Bhaskaran, Sahra Uygun, René Bernards, Laura J van ’t Veer, Annuska M Glas, Cynthia X Ma, William Audeh DESCRIPTION: Cyclin E overexpression is associated with High Risk 70-gene signature, and may indicate intrinsic resistance to CDK4/6 inhibitors The use of CDK4/6 inhibitors (CDK4/6i) is Read More

SABCS 2019: FLEX Trials in Progress

AUTHORS: Jennifer Crozier, Gordan Srkalovic, Adam Brufsky, Mehran Habibi, Pat Whitworth, Charles Cox6, Ian Grady, Thomas Lomis, Nina D’Abreo, Sarah Untch1, Erin Yoder, Heather M. Kling, William Audeh, Bastiaan van der Baan, FLEX Investigators Group DESCRIPTION: The FLEX Real World Data Platform Explores New Gene Expression Profiles and Investigator-Initiated Protocols Read More

SABCS 2019: Chinese Patient Clinical Data

AUTHORS: Ava Kwong, Sarah Untch, Heather M. Kling, Christine Finn, William Audeh, Vivian Shin, Sherene Ishtihar, Margaret Chen DESCRIPTION: Different MammaPrint and BluePrint molecular profiles and clinical-pathological features of early stage breast cancer in Chinese patients in the United States and Hong Kong Breast cancer rates among Asian women are Read More

SABCS 2019: FLEX African American Clinical Data

AUTHORS: Raquel Nunes, Dipali Sharma, Lisa E. Blumencranz, Heather M. Kling, Sahra Uygun, Andrea Menicucci, Amy Truitt, Sarah Untch, Jennifer A. Crozier, William Audeh DESCRIPTION: Racial disparities in breast cancer: identifying predisposing clinical and molecular features associated with African American patients Breast cancer (BC) mortality is higher in African-American women Read More

SABCS 2019: PROMIS Clinical Risk

AUTHORS: Michaela Tsai, Hatem Soliman, Shelly Lo, Rubina Qamar, Raye Budway, Ellis Levine, Pat Whitworth, Blanche Mavromatis, Robin Zon, Sarah Untch1, Lisa Blumencranz, Joseph McKelley, William Audeh, PROMIS Investigators Group DESCRIPTION: Treatment recommendations in ER+ patients ≤ 50 years: comparison of the 21-gene assay and 70-gene signature in the PROMIS Read More

ESMO Sept 30 Successful launch of the MammaPrint and BluePrint NGS

AUTHORS: Leonie JMJ Delahaye, Anke T Witteveen, Mireille HJ Snel1, Tyson Cavness, Bob Chan, Lorenza Mittempergher, Annuska M Glas DESCRIPTION: Successful launch of the MammaPrint and BluePrint NGS kit at decentralized sites Centralized MammaPrint (MP) and BluePrint (BP) microarray-based genomic tests on FFPE RNA were successfully translated to a targeted Read More