ADJUVANT PUBLICATIONS & ABSTRACTS

Adjuvant data


Evidence / Adjuvant

Association of 70-Gene Signature Assay Findings With Physicians’ Treatment Guidance for Patients With Early Breast Cancer Classified as Intermediate Risk by the 21-Gene Assay

PUBLICATION: JAMA Oncol. 2018; 4(1):e173470. doi:10.1001/jamaoncol.2017.3470. AUTHORS: Michaela Tsai, MD; Shelly Lo, MD; William Audeh, MD; Rubina Qamar, MD; Raye Budway, MD; Ellis Levine, MD; Pat Whitworth, MD; Blanche Mavromatis, MD; Robin Zon, MD; Dwight Oldham, MD; Sarah Untch, MS; Tina Treece, PhD; Lisa Blumencranz, PhD; Hatem Soliman, MD ABSTRACT: Read More

Impact of 70-Gene Signature Use on Adjuvant Chemotherapy Decisions in Patients With Estrogen Receptor–Positive Early Breast Cancer: Results of a Prospective Cohort Study

PUBLICATION: Journal of Clinical Oncology 35, no. 24 (August 20, 2017) 2814-2819. DOI: 10.1200/JCO.2016.70.3959. AUTHORS: Anne Kuijer, Marieke Straver, Bianca den Dekker, Annelotte C.M. van Bommel, Sjoerd G. Elias, Carolien H. Smorenburg, Jelle Wesseling, Sabine C. Linn, Emiel J.Th. Rutgers, Sabine Siesling, and Thijs van Dalen SUMMARY: Prospective, observational Dutch Read More

Characterisation of Multifocal Breast Cancer Using the 70-gene Signature in Clinical Low-Risk Patients Enrolled in the EORTC 10041/BIG 03-04 MINDACT Trial.

PUBLICATION: European Journal of Cancer. July 2017, Volume 79, Pages 98–105. AUTHORS: K.C. Aalders, A. Kuijerb, M.E. Straver, L. Slaets, S. Litiere, G. Viale, L.J. van't Veer, A.M. Glas, M. Delorenzi, T. van Dalen, K. Tryfonidis, M.J. Piccart, F. Cardoso, E.J. Rutgers on behalf of the TRANSBIG Consortium and the Read More

A Breast Cancer Gene Signature for Indolent Disease

PUBLICATION: Breast Cancer Res Treat. 2017 Oct;117(3):483-95. doi: 10.1007/s10549-008-0191-2. Epub 2008 Sep 26. AUTHORS: Leonie J.M.J. Delahaye, Caroline A. Drukker, Christa Dreezen, Anke Witteveen, Bob Chan, Mireille Snel, Inès J. Beumer, Rene Bernards, M. William Audeh, Laura J. van’t Veer, Annuska M. Glas SUMMARY: An Ultralow Risk development paper. In Read More

70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

PUBLICATION: N Engl J Med 2016; 375:717-729; DOI: 10.1056/NEJMoa1602253. AUTHORS: Fatima Cardoso, M.D., Laura J. van’t Veer, Ph.D., Jan Bogaerts, Ph.D., Leen Slaets, Ph.D., Giuseppe Viale, M.D., Suzette Delaloge, M.D., Jean-Yves Pierga, M.D., Ph.D., Etienne Brain, M.D., Ph.D., Sylvain Causeret, M.D., Mauro DeLorenzi, Ph.D., Annuska M. Glas, Ph.D., Vassilis Golfinopoulos, Read More

MINDACT Supplementary Appendix NEJM 2016

SUPPLEMENTARY APPENDIX: This appendix has been provided by the authors to give readers additional information about their work. Supplement to: Cardoso F., van’t Veer L.J., Bogaerts J., et al. 70-Gene signature as an aid to treatment decisions in early-stage breast cancer. N Engl J Med 2016;375:717-29. DOI: 10.1056/NEJMoa1602253.   Read Read More