VALIDATION PUBLICATIONS & ABSTRACTS
Validation Data
Evidence / Validation
MammaPrint Molecular Diagnostics on Formalin-Fixed, Paraffin-Embedded Tissue
PUBLICATION: J Mol Diagn. 2014 Mar;16(2):190-7. doi: 10.1016/j.jmoldx.2013.10.008. Epub 2013 Dec 28. AUTHORS: Anna Sapino, Paul Roepman, Sabine C. Linn, Mireille H.J. Snel, Leonie J.M.J. Delahaye, Jeroen van den Akker, Annuska M. Glas, Iris M. Simon, Neil Barth, Femke A. de Snoo, Laura J. van ’t Veer, Luca Molinaro, Els Read More
Long-Term Impact of the 70-Gene Signature on Breast Cancer Outcome
PUBLICATION: Breast Cancer Res Treat. 2014 Feb;143(3):587-92. doi: 10.1007/s10549-013-2831-4. Epub 2014 Jan 21. AUTHORS: Drukker C.A., van Tinteren H., Schmidt M.K., Rutgers E.J., Bernards R., van de Vijver M.J., Van't Veer L.J. SUMMARY: MammaPrint showed a significant absolute difference in DMFS and OS at 25 years between the patients with Read More
Performance Characteristics of the MammaPrint® Breast Cancer Diagnostic Gene Signature
PUBLICATION: PERSONALIZED MEDICINE VOL. 10, NO. 8 | 17 Oct 2013 https://doi.org/10.2217/pme.13.88 AUTHORS: Leonie J.M. Delahaye, Diederik Wehkamp, Arno N. Floore, Rene Bernards, Laura J. van‘t Veer & Annuska M. Glas SUMMARY: Here we study these performance characteristics of the MammaPrint® (Agendia NV, Amsterdam, The Netherlands) 70-gene signature using the Read More
Comparison of Molecular Subtyping with BluePrint, MammaPrint, and TargetPrint to Local Clinical Subtyping in Breast Cancer Patients
PUBLICATION: Ann Surg Oncol. 2012 Oct;19(10):3257-63. doi: 10.1245/s10434-012-2561-6. Epub 2012 Aug 15. AUTHORS: Nguyen B., Cusumano P.G., Deck K., Kerlin D., Garcia A.A., Barone J..L, Rivera E., Yao K., de Snoo F.A., van den Akker J., Stork-Sloots L., Generali D. SUMMARY: The concordance between BluePrint and IHC/FISH subtyping was 94% Read More
Gene Expression Profiles from Formalin Fixed Paraffin Embedded Breast Cancer Tissue are Largely Comparable to Fresh Frozen Matched Tissue
PUBLICATION: PLoS One. 2011 Feb 11;6(2):e17163. doi: 10.1371/journal.pone.0017163. AUTHORS: Mittempergher L., de Ronde J.J., Nieuwland M., Kerkhoven R.M., Simon I., Rutgers E.J., Wessels L.F., Van't Veer L.J. SUMMARY: We demonstrate that data generated from FFPE material with the DASL assay, if properly processed, are comparable to data extracted from the Read More
Biological Functions of the Genes in the MammaPrint® Breast Cancer Profile Reflect the Hallmarks of Cancer
PUBLICATION: Biomarker Insights. 2010 Nov 28;5:129-38. doi: 10.4137/BMI.S6184. AUTHORS: Tian S., Roepman P., Van't Veer L.J., Bernards R., de Snoo F., Glas A.M. SUMMARY: The study included 3090 clinical low-risk patients with unifocal and 238 patients with multifoGenes in the MammaPrint gene signature comprehensively measure the six hallmarks of cancer-related Read More
Clinical Utility of the 70-gene MammaPrint Profile in a Japanese Population
PUBLICATION: Japanese Journal of Clinical Oncology, Volume 40, Issue 6, June 2010, Pages 508–512, https://doi.org/10.1093/jjco/hyp195. AUTHORS: Makoto Ishitobi, Teodora E. Goranova, Yoshifumi Komoike, Kazuyoshi Motomura, Hiroki Koyama, Annuska M. Glas, Ellen van Lienen, Hideo Inaji, Laura J. Van't Veer, Kikuya Kato SUMMARY: A small observational study in a Japanese Cohort Read More
