ADJUVANT PUBLICATIONS & ABSTRACTS
Adjuvant data
Evidence / Adjuvant
MammaPrint Predicts Chemotherapy Benefit in HR+HER2- Early Breast Cancer: FLEX Registry Real-World Data
Publication: JNCI Cancer Spectrum, August 2025 Authors: Brufsky et al. Title: MammaPrint Predicts Chemotherapy Benefit in HR+HER2- Early Breast Cancer: FLEX Registry Real-World Data Abstract Background:ย Gene expression assays help personalize adjuvant chemotherapy decisions for hormone receptor-positive, HER2-negative (HR+HER2-) early breast cancer (EBC). The 70-gene risk of distant-recurrence signature, MammaPrint, Read More
Real-World Evidence From FLEX: Utility of MammaPrint in Guiding Treatment Planning for Patients Aged 70 and Older With Early-Stage Breast Cancer
Publication: ASCOยฎ 2025 Authors: Reshma Mahtani, Ana Sandoval-Leon, Anna Schrieber, Cathy Graham, Lauren Carcas, Naomi Dempsey, Victoria Poillucci, Michelle Landon, Christa Dreezen, William Audeh Title: Real-world Evidence from FLEX: Utility of MammaPrint in guiding treatment planning for patients aged 70 and older with early-stage breast cancer Background: Older women Read More
Survival Outcomes for Patients With Invasive Lobular Cancer by MammaPrint: Results From the MINDACT Phase III Trial
Publication: European Journal of Cancer 217 (2025) 115222 Authors: O. Metzger Filho, F. Cardoso, C. Poncet, C. Desmedt, S. Linn, J. Wesseling,F. Hilbers, S. Delaloge,ย J.-Y. Pierga, E. Brain, S. Vrijaldenhoven, P.A. Neijenhuisj, E.J.Th Rutgers, M. Piccart, L.J. van โt Veerl, G. Viale Title: Survival outcomes for patients with Read More
Prediction of Chemotherapy Benefit by MammaPrint in HR+HER2- Early Stage Breast Cancer Revealed by the FLEX Registry of Real World Data
Source:ย San Antonio Breast Cancer Symposiumยฎ Authors: Adam Brufsky*, Kent Hoskins, Henry Conter, Pond Kelemen, Mehran Habibi, Laila Samian, Robert Maganini, Rakshanda Rahman, Laura Lee, Eduardo Dias, Regina Hampton, Beth Seiling, Cynthia Osborne, Eric Brown, Jailan Elayoubi, Priyanka Sharma, Jayanthi Ramadurai, Laurie Matt-Amral, Alfredo Santillan, Sasha Strain, Philip Albaneze, Read More
Association of MammaPrint With Gene Expression Pathways Predictive of Resistance to Cyclin-Dependent Kinase Inhibition
Source:ย ย San Antonio Breast Cancer Symposiumยฎ Authors:ย Adam Brufsky, VK Gadi, Aisha Ahmed, Preethi John, Beth Seiling, Josien Haan6, Harshini Ramaswamy, Nicole Stivers, Andrea Menicucci, William Audeh, Joyce OโShaughnessy, FLEX Investigatorsโ Group Title: Association of MammaPrintยฎ With Gene Expression Pathways Predictive of Resistance to Cyclin-Dependent Kinase Inhibition Background: Cyclin-dependent kinase Read More
70โGene signatureโguided adjuvant systemic treatment adjustments in earlyโstage ER+ breast cancer patients: 7โyear followโup study
Title: 70โGene signatureโguided adjuvant systemic treatment adjustments in earlyโstage ER+ breast cancer patients: 7โyear followโup of a prospective multicenter cohort study Publication: Breast Cancer Research and Treatment 2024 Authors: Eline E. F. Verreck, Anne Kuijer, Julia E. C. van Steenhoven, Josรฉ H. Volders, Annette W. G. van der Velden, Read More
Assessing the long-term prognostic ability of the 70 gene expression signature MammaPrint in an Italian single-center prospective cohort study of early-stage intermediate-risk breast cancer patients
Publication: Heliyon 10 (2024) e39485 Authors: Daniele Generali, Andrea Rocca, Carla Strina, Manuela Milani, Enrico Fiorino Valeria Cervoni, Carlo Azzini, Antonella Saracino, Ingnazio Ciliberto, Nicoletta Ziglioli, Marzia Alberio, Fabiola Giudici, Martina Dester, Oriana Ciani, Giulia Fornaro, Sergio Aguggini, Christa Dreezen, Darina Pronin, Stefanie Ende Title:ย Assessing the long-term prognostic Read More
