PUBLICATIONS & ABSTRACTS: CLINICAL EVIDENCE
100s of extensive peer reviewed publications and studies utilizing MammaPrint + BluePrint have observed benefits from treatment in the following areas of clinical utility:
Scientific evidence for clinical utility.
By continually expanding and strengthening our database of proven research including 20+ years of clinical validation and 200+ research collaborations, we have gained widespread trust in the precision, accuracy and quality of our MammaPrintยฎ and BluePrintยฎ test suite.
Evidence
Converting a Breast Cancer Microarray Signature into a High-Throughput Diagnostic Test
PUBLICATION: BMC Genomics. 2006 Oct 30;7:278. AUTHORS:ย Glas A.M., Floore A., Delahaye L.J., Witteveen A.T., Pover R.C., Bakx N., Lahti-Domenici J.S., Bruinsma T.J., Warmoes M.O., Bernards R., Wessels L.F., Van't Veer L.J. SUMMARY:ย In this report, we demonstrate for the first time that microarray technology can be used as a Read More
Gene Expression Profiles of Primary Breast Carcinomas from Patients at High-Risk for Local Recurrence After Breast-Conserving Therapy
PUBLICATION: Clin Cancer Res. 2006 Oct 1;12(19):5705-12. AUTHORS: Kreike B., Halfwerk H., Kristel P., Glas A., Peterse H., Bartelink H., van de Vijver M.J. SUMMARY: No significant differences in gene expression between primary breast cancer tumors in patients with or without local recurrence after BCT were identified. Furthermore, analyses of Read More
Validation and Clinical Utility of a 70-Gene Prognostic Signature for Women with Node-Negative Breast Cancer
PUBLICATION: J Natl Cancer Inst. 2006 Sep 6;98(17):1183-92. AUTHORS: Buyse M., Loi S., van't Veer L., Viale G., Delorenzi M., Glas A.M., d'Assignies M.S., Bergh J., Lidereau R., Ellis P., Harris A., Bogaerts J., Therasse P., Floore A., Amakrane M., Piette F., Rutgers E., Sotiriou C., Cardoso F., Piccart M.J.; Read More
Molecular Portraits and 70-gene Prognosis Signature Are Preserved Throughout the Metastatic Process of Breast Cancer
PUBLICATION: Cancer Res. 2005 Oct 15;65(20):9155-8. AUTHORS: Weigelt B., Hu Z., He X., Livasy C., Carey L.A., Ewend M.G., Glas A.M., Perou C.M., Van't Veer L.J. SUMMARY: Furthermore, our data imply that poor prognosis breast carcinomas classified either by the intrinsic gene set or the 70 prognosis genes represent distinct Read More
Gene Expression Profiling of Breast Cancer: A New Tumor Marker
PUBLICATION: Journal of Clinical Oncology March 10, 2005 23:8, 1631-1635 AUTHORS: Laura J. van't Veer, Soonmyung Paik, Daniel F. Hayes SUMMARY: A review of genomic signatures and the genomic landscape. Read more: van't Veer et al_2005_Journal of Clinical Oncology._Gene Expression Profiling ย
A Gene-Expression Signature as a Predictor of Survival in Breast Cancer
PUBLICATION: N Engl J Med. 2002 Dec 19;347(25):1999-2009. AUTHORS: van de Vijver M.J., He Y.D., van't Veer L.J., Dai H., Hart A.A., Voskuil D.W., Schreiber G.J., Peterse J.L., Roberts C., Marton M.J., Parrish M., Atsma D., Witteveen A., Glas A., Delahaye L., van der Velde T., Bartelink H., Rodenhuis S., Read More
Gene Expression Profiling Predicts Clinical Outcome of Breast Cancer
PUBLICATION: Nature. 2002 Jan 31;415(6871):530-6. AUTHORS: van 't Veer L.J., Dai H., van de Vijver M.J., He Y.D., Hart A.A., Mao M., Peterse H.L., van der Kooy K., Marton M.J., Witteveen A.T., Schreiber G.J., Kerkhoven R.M., Roberts C., Linsley P.S., Bernards R., Friend S.H. SUMMARY: Development of MammaPrint from 98 Read More
