Clinical and Scientific Evidence for MammaPrint + BluePrint

Evidence

ASCO 2020: HER2 Reclassification

PUBLICATION: ASCO 20 AUTHORS: Adam Brufsky, Jennifer A. Crozier, Paul J. Chuba, Sung Ho Lee, Andrea Menicucci, Heather M. Kling, Erin Yoder, William Audeh, FLEX Investigators' Group SUMMARY: Biological heterogeneity of HER2 positive breast cancers is supported by a modest benefit of HER2- targeted therapies reported in the APHINITY and Read More

ASCO 2020: FLEX Trials in Progress

PUBLICATION: ASCO 20 AUTHORS: Nina D’Abreo, Jennifer Crozier, Adam Brufsky, Ian Grady, Sami Diab, Blanche Mavromatis, Carrie Dul, Rakhshanda Layeequr Rahman, Laura Lee, Vijayakrishna K. Gadi1, Sarah Untch, Erin Yoder, Heather M. Kling, Amy M. Truitt, William Audeh, Bastiaan van der Baan, FLEX Investigators Group SUMMARY: Genomic expression profiles have Read More

Miami Breast 2020 FLEX Trials in Progress

AUTHORS: Robert Maganini, Pond Kelemen, Jennifer A. Crozier, Gordan Srkalovic, Adam Brufsky, Mehran Habibi, Ian Grady, Nina D’Abreo, Michelle Bolner, Sarah Untch, Erin Yoder, Heather M. Kling, William Audeh, Bastiaan van der Baan FLEX Investigators Group DESCRIPTION: The FLEX Real World Data Platform Explores New Gene Expression Profiles and Investigator-Initiated Read More

SABCS 2019: Cyclin E Expression

AUTHORS: Lorenza Mittempergher, Joseph McKelley, Rajith Bhaskaran, Sahra Uygun, René Bernards, Laura J van ’t Veer, Annuska M Glas, Cynthia X Ma, William Audeh DESCRIPTION: Cyclin E overexpression is associated with High Risk 70-gene signature, and may indicate intrinsic resistance to CDK4/6 inhibitors The use of CDK4/6 inhibitors (CDK4/6i) is Read More

SABCS 2019: FLEX Trials in Progress

AUTHORS: Jennifer Crozier, Gordan Srkalovic, Adam Brufsky, Mehran Habibi, Pat Whitworth, Charles Cox6, Ian Grady, Thomas Lomis, Nina D’Abreo, Sarah Untch1, Erin Yoder, Heather M. Kling, William Audeh, Bastiaan van der Baan, FLEX Investigators Group DESCRIPTION: The FLEX Real World Data Platform Explores New Gene Expression Profiles and Investigator-Initiated Protocols Read More