Clinical and Scientific Evidence for MammaPrint + BluePrint

Evidence

Miami Breast 2020 FLEX Trials in Progress

AUTHORS: Robert Maganini, Pond Kelemen, Jennifer A. Crozier, Gordan Srkalovic, Adam Brufsky, Mehran Habibi, Ian Grady, Nina D’Abreo, Michelle Bolner, Sarah Untch, Erin Yoder, Heather M. Kling, William Audeh, Bastiaan van der Baan FLEX Investigators Group DESCRIPTION: The FLEX Real World Data Platform Explores New Gene Expression Profiles and Investigator-Initiated [Read More]

MammaPrint guides treatment decisions in breast Cancer: results of the IMPACt trial

PUBLICATION: Soliman et al. BMC Cancer (2020) 20:81 AUTHORS: Hatem Soliman, Varsha Shah, Gordan Srkalovic, Reshma Mahtani, Ellis Levine, Blanche Mavromatis, Jayanthi Srinivasiah, Mohamad Kassar, Robert Gabordi, Rubina Qamar, Sarah Untch, Heather M. Kling, Tina Treece1, William Audeh SUMMARY: Results from the IMPACt trial measured changes in both treatment decisions [Read More]

SABCS 2019: Cyclin E Expression

AUTHORS: Lorenza Mittempergher, Joseph McKelley, Rajith Bhaskaran, Sahra Uygun, René Bernards, Laura J van ’t Veer, Annuska M Glas, Cynthia X Ma, William Audeh DESCRIPTION: Cyclin E overexpression is associated with High Risk 70-gene signature, and may indicate intrinsic resistance to CDK4/6 inhibitors The use of CDK4/6 inhibitors (CDK4/6i) is [Read More]

SABCS 2019: FLEX Trials in Progress

AUTHORS: Jennifer Crozier, Gordan Srkalovic, Adam Brufsky, Mehran Habibi, Pat Whitworth, Charles Cox6, Ian Grady, Thomas Lomis, Nina D’Abreo, Sarah Untch1, Erin Yoder, Heather M. Kling, William Audeh, Bastiaan van der Baan, FLEX Investigators Group DESCRIPTION: The FLEX Real World Data Platform Explores New Gene Expression Profiles and Investigator-Initiated Protocols [Read More]

SABCS 2019: Chinese Patient Clinical Data

AUTHORS: Ava Kwong, Sarah Untch, Heather M. Kling, Christine Finn, William Audeh, Vivian Shin, Sherene Ishtihar, Margaret Chen DESCRIPTION: Different MammaPrint and BluePrint molecular profiles and clinical-pathological features of early stage breast cancer in Chinese patients in the United States and Hong Kong Breast cancer rates among Asian women are [Read More]

SABCS 2019: FLEX African American Clinical Data

AUTHORS: Raquel Nunes, Dipali Sharma, Lisa E. Blumencranz, Heather M. Kling, Sahra Uygun, Andrea Menicucci, Amy Truitt, Sarah Untch, Jennifer A. Crozier, William Audeh DESCRIPTION: Racial disparities in breast cancer: identifying predisposing clinical and molecular features associated with African American patients Breast cancer (BC) mortality is higher in African-American women [Read More]

SABCS 2019: PROMIS Clinical Risk

AUTHORS: Michaela Tsai, Hatem Soliman, Shelly Lo, Rubina Qamar, Raye Budway, Ellis Levine, Pat Whitworth, Blanche Mavromatis, Robin Zon, Sarah Untch1, Lisa Blumencranz, Joseph McKelley, William Audeh, PROMIS Investigators Group DESCRIPTION: Treatment recommendations in ER+ patients ≤ 50 years: comparison of the 21-gene assay and 70-gene signature in the PROMIS [Read More]