PUBLICATION:
J Mol Diagn. 2014 Mar;16(2):190-7. doi: 10.1016/j.jmoldx.2013.10.008. Epub 2013 Dec 28.

AUTHORS:
Anna Sapino, Paul Roepman, Sabine C. Linn, Mireille H.J. Snel, Leonie J.M.J. Delahaye, Jeroen van den Akker, Annuska M. Glas, Iris M. Simon, Neil Barth, Femke A. de Snoo, Laura J. van ’t Veer, Luca Molinaro, Els M.J.J. Berns, Jelle Wesseling, Lee B. Riley, David Anderson, Bichlien Nguyen, Charles E. Cox

SUMMARY:
MammaPrint-FFPE indices showed a high correlation with the matching indices for fresh tissue samples (r Z 0.917; 95% CI, 0.893e0.936) (Figure 3). Concordance of categorical low-risk and high-risk classification was 91.5% (95% CI, 86.9%e94.5%) in this validation set; the NPA was 91.3% (95% CI, 84.4%e95.4%) and the PPA was 91.6% (95% CI, 84.8%e95.5%). A k score of 0.82 (95% CI, 0.74e0.89) indicated “an almost perfect agreement”.

Read more: MammaPrint Molecular Diagnostics on Formalin-Fixed…_Sapino_J Mol Diagn. 2014